Tietz Fundamentals of Clinical Chemistry

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A practical guide to using chemistry in the clinical laboratory! Inside this condensed, reader-friendly version of Tietz Textbook of Clinical Chemistry, you'll find the chemistry fundamentals you need to know, explained from a real-world laboratory perspective. Offering complete, accurate coverage of chemical structures and key topics in the field, it's everything that you expect fro the authority in clinical chemistry! Inside you'll find. A new introductory chapter, Introduction to Clinical Chemistry and Evidence-Based Laboratory Medicine, to give you a helpful overviewof key topics. A new chapter on newborn screening that discusses the basic principles, screening recommendations, inborn errors, methods, and interpretation of results. A new chapter on point-of-care testing that covers the technology available and the organizational factors that are important when point-of-care testing is implemented in a healthcare setting. More than 500 illustrations and easy-to-read tables to help you understand and remember key concepts. Key words, learning objectives, and other student-friendly features that reinforce important material. A comprehensive glossary to provide quick access to definitions of key terms. Chapter review questions to test your knowledge. Key Features More than 500 illustrations and easy-to-read tables help you understand and remember key concepts. Key words, learning objectives, and other student-friendly features reinforce important material Chapter review questions are included in an appendix to test your knowledge. A two-color design makes it easier to read and easy to find important topics. In-depth, reader-friendly content is appropriate for MT/CLS and MLT/CLT students and may also be used by laboratory practitioners, pathology residents, and others.

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Carl A. Burtis PhD, Chief, Clinical Chemistry, Health Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT. Edward R. Ashwood, MD, Professor of Pathology, University of Utah, and Laboratory Director, ARUP Laboratories, Salt Lake City, UT. David E. Bruns, MD, Professor of Pathology, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia, Charlottesville, VA, and Editor, Clinical Chemistry, Washington, DC. Table of Contents I. LABORATORY PRINCIPLES 1. Introduction to Clinical Chemistry and Evidence-Based Laboratory Medicine 2. Introduction to Principles of Laboratory Analyses and Safety 3. Specimen Collection and Other Pre-Analytical Variables II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION 4. Optical Techniques 5. Electrochemistry and Chemical Sensors 6. Electrophoresis 7. Chromatography 8. Mass Spectrometry 9. Principles of Clinical Enzymology 10. Principles of Immunochemical Techniques 11. Automation in the Clinical Laboratory 12. Point-of-Care Testing III. LABORATORY OPERATIONS 13. Selection and Analytical Evaluation of Methods — With Statistical Techniques 14. Establishment and Use of Reference Values 15. Clinical Laboratory Informatics 16. Quality Management IV. ANALYTES 17. Nucleic Acids 18. Amino Acids and Proteins 19. Enzymes 20. Tumor Markers 21. Creatinine, Uric acid, and Urea 22. Carbohydrates 23. Lipids, Lipoproteins, and Cardiac Risk Factors 24. Electrolytes and Blood Gases 25. Hormones 26. Catecholamines and Serotonin 27. Vitamins and Trace Elements 28. Hemoglobin, Iron, and Bilirubin 29. Porphyrins and Disorders of Porphyrin Metabolism 30. Therapeutic Drugs 31. Clinical Toxicology 32. Toxic Metals V. PATHOPHYSIOLOGY 33. Cardiovascular Disease 34. Renal Disease 35. Disorders of Water, Electrolyte, and Acid-Base Metabolism 36. Liver Disease 37. Gastric, Pancreatic, and Intestinal Diseases 38. Disorders of Bone 39. Pituitary Disorders 40. Adrenal Cortical Disorders 41. Thyroid Disorders 42. Reproductive Disorders 43. Disorders of Pregnancy 44. Newborn Screening VI. REFERENCE INFORMATION 45. Reference Information for the Clinical Laboratory Appendix: Review Questions Glossary