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Metal Sites in Proteins and Models: Phosphatases, Lewis Acids and Vanadium 4.0%OFF

Metal Sites in Proteins and Models: Phosphatases, Lewis Acids and Vanadium

by H. A. Hill, P. J. Sadler and A. J. Thomson

  • ISBN

    :  

    9783540655534

  • Publisher

    :  

    Springer

  • Subject

    :  

    Chemistry

  • Binding

    :  

    Paperback

  • Pages

    :  

    205

  • Year

    :  

    1999

10151.0

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  • Description

    Biological chemistry is a major frontier of inorganic chemistry. Three special volumes devoted to Metal Sites in Proteins and Models address the questions: how unusual ("entatic") are metal sites in metalloproteins and metalloenzymes compared to those in small coordination complexes? and if they are special, how do polypeptide chains and co-factors control this? The chapters deal with iron, with metal centres acting as Lewis acids, metals in phosphate enzymes, with vanadium, and with the wide variety of transition metal ions which act as redox centres. They illustrate in particular how the combined armoury of genetics and structure determination at the molecular level are providing unprecedented new tools for molecular engineering.

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